Medical Science Liaison (MSL) - Hematology
Job Opportunity at Spark Therapeutics, Inc

Posted on May 11

http://www.sparktx.com    215-220-9300

Location: Philadelphia, PA
Job Type: Full Time
Job ID: W4159443

The Medical Science Liaison (MSL) will be responsible for providing non-promotional scientific, educational, and research support for Spark Therapeutic gene therapy portfolio in the respective territory.  The MSL position is a field based member of the Medical Affairs team. The MSL should be highly trained in a health care field and well versed in clinical practice and basic science. The MSL should be able to deliver cutting edge data and technical/practical education to Health Care Professionals (HCPs).
The MSL will be responsible for developing and maintaining relationships with key gene therapy experts and building a well-informed advocacy base for the Spark Therapeutic franchise, including compounds in the development program. The MSL will act as a conduit for providing accurate and updated clinical, scientific and medical information to gene therapy experts, health care professionals, treatments decision makers and other members of the scientific, provider and payer community (private insurance, payers, medical groups, government agencies, and health systems with drug formularies), in compliance with all relevant company policies.
This territory is flexible depending on the candidate selected.

  • Maintains business and clinical knowledge of the gene therapy treatment landscape including current treatment strategies, current and pending competitors, and new therapeutic developments.
  • Increases Spark's visibility among leaders in the therapeutic field of Hemophilia. Identifies, establishes and maintains collaborative relationships with key experts, investigators and institutions strategic to product development.
  • Participates in medical education for healthcare professionals through presentations at office visits, investigator meetings, advisory boards, medical meetings, and other appropriate venues to enhance product and disease state knowledge.
  • Collaborates with clinical team and CRA's to coordinate and optimize educational and research support for sites/investigators participating in Spark's clinical trials.
  • Responds to unsolicited requests regarding interest in investigator sponsored studies (ISS), and supports ISS submissions through appropriate internal processes. 
  • Responds to unsolicited request for medical information associated with supported products and disease state areas.
  • Provides effective clinical presentations to internal and external audiences and tailors presentations to meet specific needs of the audience (appropriate response to unsolicited requests).
  • Identifies and communicates key clinical and research issues and insights from industry leaders to appropriate departments to help shape company research, development, and strategies for investigational and commercialized products.
  • Facilitates the identification of medical community educational needs around disease state management, including awareness and understanding of appropriate/inappropriate use of company products.
  • Collaborates with internal and external stakeholders in support of needs of Key
  • Opinion leaders (KOLs).
  • Maintains clinical expertise through comprehensive education including attendance at relevant symposia, scientific workshops, and review of key journals. Participation in required internal training, presentations and journal clubs.
  • Maintains appropriate communication with Medical, Regulatory, and Legal personnel within the company to ensure appropriate timelines and procedures are met. 
  • Adheres to regulatory and compliance guidelines and company policies in all aspects of scientific dissemination of information to include responses to unsolicited requests for medical information.
  • Enhances clinical/scientific knowledge of customers and colleagues through education and appropriate scientific exchange.
  • Works collaboratively with relevant internal stakeholders to identify local/regional educational gaps/needs and apply appropriate field medical support that is aligned with medical strategy.
  • Provides field updates regarding topics of interest.
  • Addresses administrative and reporting needs on a timely basis or as requested by management.
  • Provides clinical presentations to Payer groups as requested.
  • Understanding and ability to implement field medical tactics/activities which include, but not limited to:
    • Disease state, current therapies, outcomes, and basic health economic parameters.
    • Understanding of highly regulated pharmaceuticals environment.
    • Ability to initiate and maintain relationships with medical community.

Basic Qualifications
  • Minimum requirements include:
  • Master's degree in a life science subject and 3 or more years related pharma/biotech experience or 5 years in a biotechnology clinical environment.
Preferred Qualifications
  • PharmD, MD, PhD, or Master Level Genetic Counselor’s degree or other doctoral-level degree preferred and 2 years related pharma/biotech experience.  Consideration will be given to candidates with advanced health care degrees and relevant industry/clinical experience.
  • Knowledge and experience in field medical Orphan Diseases (gene therapy, genetics, lysosomal storage diseases and/or hepatology, etc.) preferred.
  • Knowledge and experience in disease area preferred.
  • Preferred previous pharmaceutical industry experience.
  • Clear understanding of regional medical practice and clinical decision making regards to patient care.
  • Ability to identify the unmet medical, educational, and research needs within the regional medical community.
  • Interpretation of key scientific data and ability to translate this information to meet educational and research needs.
  • Demonstrated ability to address educational and research needs through delivery of cutting edge scientific/evidenced based data.
  • Understanding of healthcare systems affecting patient care.
  • Understanding of the design and execution of research studies.
  • Exemplary communication and presentation skills.
  • Ability to think strategically.


Transforming Patient’s Lives. Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team.

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